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Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 651-658 doi: 10.1007/s11684-021-0859-0

Abstract: To present the clinical characteristics and the misdiagnosis rate of acute coronary syndrome manifestedcoronary syndrome, as well as patients with pharyngitis (as controls) were collected from May 2015 toA total of 25 (56.82%) out of 44 acute coronary syndrome patients, who were first admitted to the otorhinolaryngologyThroat discomfort can be the principal manifestation of acute coronary syndrome.coronary syndrome in patients whose main complaint was throat discomfort.

Keywords： acute coronary syndrome (ACS)     throat discomfort (TD)     throat pain     cardiology departments     non-cardiologic    

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The early percutaneous coronary intervention in elderly patients with acute coronary syndrome

HUANG Xiong, CAO Xuebin, ZHANG Gang

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 15-18 doi: 10.1007/s11684-008-0004-3

Abstract: It is challenging to undo early percutaneous intervention (PCI) in the elderly with acute coronary syndrome(ACS).Fifteen patients older than 65 years with ACS within 24 hours of the event were admitted from April 4All the patients had early percutaneous coronary intervention and were followed up for 6–12 months byNine of the 15 patients exhibited acute myocardial infarction (AMI).

Keywords： door-to-balloon     percutaneous intervention     coronary syndrome     angioplasty     successful    

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Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 296-301 doi: 10.1007/s11684-012-0219-1

Abstract: improved the development of modern cardiac surgery, many factors during CPB have been reported to induce acuterespiratory distress syndrome (ARDS).

Keywords： tumor necrosis factor-α     cardiopulmonary bypass     inflammation     acute respiratory distress syndrome    

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A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Frontiers of Medicine doi: 10.1007/s11684-023-1011-0

Abstract: efficacy of nirmatrelvir/ritonavir (Paxlovid) therapy for hemodialysis-dependent patients with severe acuterespiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Keywords： Paxlovid     hemodialysis     SARS-CoV-2     viral load     chest CT scan    

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Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris

Yufeng Zhao, Xueyun Yu, Xinyu Cao, Lin Luo, Liyun He, Shusong Mao, Li Ma, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 566-571 doi: 10.1007/s11684-017-0556-1

Abstract:

Syndromes of coronary heart disease with angina pectoris were analyzed to provide guidance for clinicalA total of 860 cases with coronary heart disease with angina pectoris were selected from TCM ClinicalFinal syndrome classifications were recognized and confirmed by clinical experts.The main syndrome elements comprised Qi deficiency, blood deficiency, blood stasis, and Qi stagnation

Keywords： syndrome differentiation     real-world study     coronary heart disease with angina pectoris     cluster analysis    

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Contemporary coronary artery bypass grafting

David P. Taggart

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 395-398 doi: 10.1007/s11684-014-0374-7

Abstract:

Current evidence clearly demonstrates that coronary artery bypass grafting (CABG) remains the &ldquo

Keywords： coronary artery bypass grafting (CABG)     coronary artery disease     left main     arterial grafts     internal mammary    

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Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 238-249 doi: 10.1007/s11684-017-0599-3

Abstract: The efficacy of salvage interferon-α (IFN-α) treatment was investigated in patients with unsatisfactory response to minimal residual disease (MRD)-directed donor lymphocyte infusion (DLI) ( =24). Patients who did not become MRD-negative at 1 month after DLI were those with unsatisfactory response and were eligible to receive salvage IFN-α treatment within 3 months of DLI. Recombinant human IFN-α-2b injections were subcutaneously administered 2–3 times a week for 6 months. Nine (37.5%), 6 (25.0%), and 3 (12.5%) patients became MRD-negative at 1, 2, and>2 months after the salvage IFN-α treatment, respectively. Two-year cumulative incidences of relapse and non-relapse mortality were 35.9% and 8.3%, respectively. Two-year probabilities of event-free survival, disease-free survival, and overall survival were 51.6%, 54.3%, and 68.0%, respectively. Outcomes of patients subjected to salvage IFN-α treatment after DLI were significantly better than those with persistent MRD without IFN-α treatment. Moreover, clinical outcomes were comparable between the salvage DLI and IFN-α treatment groups. Thus, salvage IFN-α treatment may help improve the outcome of patients with unsatisfactory responses to MRD-directed DLI and could be a potential salvage treatment for these patients after allogeneic hematopoietic stem cell transplantation.

Keywords： interferon-α     hematopoietic stem cell transplantation     minimal residual disease     donor lymphocyte infusion    

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Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 75-84 doi: 10.1007/s11684-022-0950-1

Abstract: retrospective single-center registry study included all consecutive patients who underwent percutaneous coronaryintervention (PCI) for a de novo left main coronary artery lesion using drug coated-balloon (Sixty-six patients (mean age 75±8.6, 72% male), 52% of whom had acutecoronary syndrome, underwent left main PCI with the DCB-only strategy.No procedural mortality and no acute closures of the treated left main occurred.

Keywords： drug-coated balloon     left main     high bleeding risk     predilatation     calcifield lesion     percutaneous coronary    

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Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 53-61 doi: 10.1007/s11684-017-0502-2

Abstract:

Low adherence to secondary prevention medications (ATM) of patients after acute coronary syndrome(ACS) is associated with poor clinical outcomes.provides limited data on assessment of ATM and risks associated with poor in Chinese patients with ACSIn the current work, ATM was assessed in consecutively recruited patients with ACS in Tongji HospitalResults showed that coronary artery bypass grafting (CABG) alone had significantly lower proportion of

Keywords： acute coronary syndromes     adherence to secondary prevention medications     clinical outcome    

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Coronary leukocyte activation in relation to progression of coronary artery disease

Marijke A. de Vries,Arash Alipour,Erwin Birnie,Andrew Westzaan,Selvetta van Santen,Ellen van der Zwan,Anho H. Liem,Noëlle van der Meulen,Manuel Castro Cabezas

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 85-90 doi: 10.1007/s11684-016-0435-1

Abstract: We evaluated the predictive value for progression of coronary artery disease (CAD) of leukocyte activationmarkers in the coronary circulation.neutrophil CD11b, neutrophil CD66b expression and intracellular neutrophil myeloperoxidase (MPO) in the coronaryarteries were determined by flow cytometry in patients undergoing coronary angiography.These data indicate that coronary monocyte CD11b, neutrophil CD11b and CD66b expression and intracellular

Keywords： coronary artery disease     inflammation     integrin     myeloperoxidase     leukocyte activation    

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Translational research on novel drug-eluting stents in percutaneous coronary intervention

Yaling Han, Kai Xu, Chenghui Yan

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 395-400 doi: 10.1007/s11684-011-0167-1

Abstract: Although first-generation drug-eluting stents (DES) have markedly reduced restenosis, complications of late and very late in-stent thrombosis have emerged as prime limitations to this technology. The development of new DES is a key process to prevent these complications. Translational research plays a very important role in experiments which determine the safety and efficacy of DES before human clinical trials. The present review focuses on translational research of novel DES, including drug discovery, creation of preclinical research models, planning and conducting of first-in-man studies, and developing next-generation DES systems.

Keywords： translational research     drug-eluting stents     percutaneous coronary intervention    

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Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute RespiratoryDistress Syndrome

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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Right coronary occlusion following transcatheter aortic valve implantation: two case reports

Gang Zhang,Jun Luo,Guo Chen

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 351-355 doi: 10.1007/s11684-016-0465-8

Abstract:

This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries

Keywords： aortic stenosis     transcatheter aortic valve implantation     right coronary occlusion     cardiac group    

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Evaluation of the effect of myocardial perfusion after percutaneous coronary intervention in coronary

WANG Hong, HUANG Lan, JIN Jun, SONG Yaoming, GENG Zhaohua, YU Xuejun, QIN Jun, ZHAO Gang, GAO Yunhua, LIU Zheng

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 62-67 doi: 10.1007/s11684-007-0013-7

Abstract: disease (CAD) after they have undergone percutaneous coronary intervention (PCI).results: group A (normal coronary artery), group B (75% 95% coronary artery stenosis), group C (coronaryartery stenosis >95%) and group D (acute total coronary occlusion).For those patients with acute or total occlusion, the levels of myocardial perfusion before and afterfor those with acute myocardial infarction (AMI).
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Title Author Date Type Operation

Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Journal Article

The early percutaneous coronary intervention in elderly patients with acute coronary syndrome

HUANG Xiong, CAO Xuebin, ZHANG Gang

Journal Article

Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Journal Article

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Journal Article

Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris

Yufeng Zhao, Xueyun Yu, Xinyu Cao, Lin Luo, Liyun He, Shusong Mao, Li Ma, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Journal Article

Contemporary coronary artery bypass grafting

David P. Taggart

Journal Article

Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Journal Article

Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

Journal Article

Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Journal Article

Coronary leukocyte activation in relation to progression of coronary artery disease

Marijke A. de Vries,Arash Alipour,Erwin Birnie,Andrew Westzaan,Selvetta van Santen,Ellen van der Zwan,Anho H. Liem,Noëlle van der Meulen,Manuel Castro Cabezas

Journal Article

Translational research on novel drug-eluting stents in percutaneous coronary intervention

Yaling Han, Kai Xu, Chenghui Yan

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute RespiratoryDistress Syndrome

Xuan Zhao, Yi Zhang

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

Right coronary occlusion following transcatheter aortic valve implantation: two case reports

Gang Zhang,Jun Luo,Guo Chen

Journal Article

Evaluation of the effect of myocardial perfusion after percutaneous coronary intervention in coronary

WANG Hong, HUANG Lan, JIN Jun, SONG Yaoming, GENG Zhaohua, YU Xuejun, QIN Jun, ZHAO Gang, GAO Yunhua, LIU Zheng

Journal Article